Jelena Samonina-Kosicka Visiting Assistant Professor of Chemistry and Biochemistry

Jelena Samonina-Kosicka

Science Addition A413
samonina-kosickaj@wlu.edu

Professional Affiliations

  • American Association for the Advancement of Science 2014-present
  • American Chemical Society 2012-present
  • Polish Chemical Society 2004-present

Education

2014 - 2016 Stanford University, Stanford, CA

  • Postdoctoral Fellow with Dr. Robert M. Waymouth Laboratory
  • Designed, synthesized and developed organometallic catalysts for the homogenous electroreduction of CO2.

2012 - 2014 University of Virginia, Charlottesville, VA

  • Postdoctoral Research Associate with Dr. Cassandra. L. Fraser
  • Designed and synthesized luminescent biocompatible nanoparticles for targeted tumor hypoxia imaging.

2012 Visiting Research Fellow

  • National Institutes of Health, Bethesda, MD

2006 - 2010 Warsaw University, Warsaw, Poland

  • Ph.D., Bioorganic Chemistry with Dr. Marianna Kanska
  • Designed, synthesized and radiolabeled with radioisotopes (2H, 3H, 14C) biologically active amino acids and biogenic amines. Stereospecific labeled compounds applied in the active sites and mechanistic studies of diamine oxidases.
  • Studied the mechanism of the biotransformation of the diamine oxidase. Designed and synthesized radiolabeled precursors (using classical synthesis tools and biocatalysis tools) for in vivo imaging by PET.

2001 - 2006 Warsaw University, Warsaw, Poland

  • M.S. with Dr. Marzena Janskowska-Anyszka
  • Synthesized a new class of ribose-functionalized dinucleotide mRNA cap analogues and applied for synthesis of the affinity chromatography resin. Studied interaction between mRNA cap and eIF4E protein.

Research

  • Nanotechnology
  • Macromolecule self-assembly

Teaching

2016–present, Washington and Lee University

• 241 Organic Chemistry I (Lecture and Lab)
• 242 Organic Chemistry (Lecture and Lab)
• 347 Advanced Organic Chemistry

2006–2013, Warsaw University, Department of Chemistry

• Organic Chemistry Lab
• Organic Chemistry Seminar

2010-2012, Medical University of Warsaw, Division of Physiotherapy

• Organic Chemistry
• Biochemistry
• Biochemistry Lab
• Chemistry for Non-Chemists

Selected Publications

Sawyer C. W., Suffield B. H., Finnefrock A. C., Billings H. M., Uffelman E. S., Zoeller J. R., Dombrowski M. S., Delaney J.K., Dooley K. A., Mass J. L., Samonina-Kosicka J., Whitesell M. M., Hyperspectral Imaging, Multispectral Imaging And X-Ray Ragiography Of A John White Alexander Painting At The Virginia Museum Of Fine Arts: Comparison Of Methodologies For Resolving A Painting Underneath Another Painting – 2018 submitted

De Crisci A. G., Samonina-Kosicka J., Gieleciak R., Fleischauer M., Morris R. H., Waymouth R. M., Electrocatalytic Transfer Hydrogenation for Carbon Dioxide (CO2) Activation and Utilization” - Poster won first prize at the Connaught Global Challenge Symposium on CO2 Solution to Climate Change.

Samonina-Kosicka, J.; Rudenko, A.; Clark, M.; Kubiak, C.; Waymouth, R. M., Mn Tricarbonyl Chloride Azopyridine Complexes for Impoved Electrochemical Reduction of CO2 – in preparation

Samonina-Kosicka, J.; Clark, M.; Rudenko, A.; Kubiak, C.; Waymouth, R. M., New Molecular Catalyst Development for Electrochemical CO2 Reduction by Re Tricarbonyl Chloride Azopyridine Complexes – in preparation

Butler, T.; Morris, W.; Samonina-Kosicka, J.; Fraser, C., Mechanochromic Luminescence and Aggregation Induced Emission of Dinaphthoylmethane β-Diketones and their Boronated Counterparts – ACS Applied Materials & Interfaces. 2016, 8, 1242–1251

Samonina-Kosicka, J.; Weitzel, D. H.; Hofmann, C. L.; Hendargo, H.; Hanna, G.; Dewhirst, M. W.; Palmer, G. M.; Fraser, C. L., Luminescent Difluoroboron β-Diketonate PEG-PLA Oxygen Nanosensors for Tumor Imaging. Macromolecular Rapid Communications 2015, 36, 694-699.

Butler, T.; Morris, W. A.; Samonina-Kosicka, J.; Fraser, C. L., Mechanochromic Luminescence and Aggregation Induced Emission for a Metal-Free Beta-Diketone. Chemical Communications 2015, 51, 3359-3362. - highlighted as "Noteworthy Chemistry" by ACS

DeRosa, C. A.; Samonina-Kosicka, J.; Fan, Z.; Hendargo, H. C.; Weitzel, D. H.; Palmer, G. M.; Fraser, C. L., Oxygen Sensing Difluoroboron Dinaphthoylmethane Polylactide. Macromolecules 2015, 48, 2967-2977.

Samonina-Kosicka, J.; DeRosa, C. A.; Morris, W. A.; Fan, Z.; Fraser, C. L., Dual-Emissive Difluoroboron Naphthyl-Phenyl β-Diketonate Polylactide Materials: Effects of Heavy Atom Placement and Polymer Molecular Weight. Macromolecules 2014, 47, 3736-3746.

Yuan, H.; Hofmann, C. L.; Samonina-Kosicka, J.; Hendargo, H.; Hanna, G.; Vo-Dinh, T.; Fraser, C. L.; Dewhirst, M. W.; Palmer, G. M., Monitoring Tumor Microenvironment (Hb Saturation And Oxygenation) in Response to Plasmonics-Assisted Photothermal Cancer Therapy. Molecular Cancer Therapeutics 2013, 12, B151.

Samonina-Kosicka, J.; Kańska, M., Synthesis of Selectively Labeled Histidine and its Methylderivatives with Deuterium, Tritium, and Carbon-14. Journal of Labelled Compounds and Radiopharmaceuticals 2013, 56, 317-320.

Samonina-Kosicka, J.; Kańska, M., Mechanistic Studies of Reactions Catalysed by Diamine Oxidase Using Isotope Effects. Isotopes in Environmental and Health Studies 2013, 49, 357-364.

Jankowska-Anyszka, M.; Piecyk, K.; Samonina-Kosicka, J., Synthesis of a New Class of Ribose Functionalized Dinucleotide Cap Analogues for Biophysical Studies on Interaction of Cap-Binding Proteins with the 5' end of mRNA. Organic & Biomolecular Chemistry 2011, 9, 5564-5572.

Kańska, M.; Pajak, M.; Panufnik, E.: Samonina-Kosicka, J.; Enzymatic Synthesis of 2H, and 3H – Labeled Biogenic Amines, Journal of Labelled Compounds and Radiopharmaceuticals 2010, 53: 275-282.

Samonina, J.; Kańska, M., Enzymatic Synthesis of N-Methylhistamine Labeled with Deuterium and Tritium. Journal of Labelled Compounds and Radiopharmaceuticals 2009, 52, 372-375.

 

Talks and Conferences

Invited Talks

  • Stanford University, Stanford Polymer Collective: “Luminescent Dye-Polymer Materials” (01/2015)
  • University of Virginia, popular-science lecture: “Chemistry of Love” (02/2014)
  • University of Virginia, Postdoc Day (won pre-selection for oral presentation): “Synthesis of Luminescent Dye Nanosensors for Tumor Hypoxia Imaging” (05/2013)

National and International Conferences (selected from over 28 meetings)

Samonina-Kosicka, J.; Rudenko, A.; Clark, M.; Kubiak, C.; Brown, T. A., Zare R. N., Waymouth, R. M., “Mechanistic Studies of the CO2 Electrochemical Reduction by the New Rhenium Tricarbonyl Azopyridine Complexes” 30th Annual Johnson Symposium, Stanford, CA, October 2015.

Samonina-Kosicka, J.; Waymouth, R. M. “Electrochemical Catalysis of CO2 Reduction by Re and Mn Tricarbonyl Halide Azopyridine Complexes” 250th ACS National Meeting and Exposition, Boston, MA, August 2015.

Samonina-Kosicka, J.; DeRosa, C. A.; Hofmann, C. L.; Hendargo, H.; Dewhirst, M. W.; Palmer, G. M., Fraser C. L. “Boron Nanoparticles for Oxygen Sensing: Material Design, Optical Properties and Bioimaging” 248th ACS National Meeting and Exposition, San Francisco, CA, August 2014.

Samonina-Kosicka, J.; Fraser C. L. “Energy Transfer and Oxygen Sensing Range Modulation in Luminescent Boron beta-Diketonate-PLA Hybrid Nanoparticles” 248th ACS National Meeting and Exposition, San Francisco, CA, August 2014.

Butler, T.P.; Samonina-Kosicka, J.; Morris, W. A.; Fraser, C. L. “Mechanochromic Luminescence and Aggregation Induced Emission of Naphthyl beta-Diketones and their Boron Difluoride Complexes” 247th ACS National Meeting and Exposition, Dallas, TX, March 2014.

DeRosa C. A.; Samonina-Kosicka, J.; Morris, W. A.; Fan, Z.; Fraser, C. L. “Effects of Heavy Atom Placement and Polymer Molecular Weight on Dual Emissive Difluoroboron Naphthyl beta-Diketonate Polylactide Materials” 247th ACS National Meeting and Exposition, Dallas, TX, March 2014.

Yuan, H.; Hofmann, C. L.; Samonina-Kosicka, J.; Hendargo, H.; Hanna, G.; Vo-Dinh, T.; Fraser, C. L.; Dewhirst, M. W.; Palmer, G. M. “Monitoring Tumor Microenvironment (Hb Saturation and Oxygenation) in Response to Plasmonics-Assisted Photothermal Cancer Therapy” AACR-NCI-EORTC International Conference: Molecular Targets and Cancer Therapeutics; Boston, MA, October 2013.

Palmer G. M.; Yuan, H. S.; Hofmann, C. L.; Samonina-Kosicka, J.; Vo-Dinh, T.; Dewhirst, M. W.; Fraser, C. L. “Boron Nanoparticles for Oxygen Sensing Using Window Chamber Tumor Models” 41st Annual ISOTT (The International Society on Oxygen Transport to Tissue) Meeting & EPR (Electron Paramagnetic Resonance) 2013, Hanover, NH, June 2013.

Samonina-Kosicka, J.; Kanska, M. “Enzymatic Synthesis of 2H, and 3H-Labeled Biogenic Amines,” 10th International Symposium of the International Isotope, Chicago, IL, June 2009.

Awards

  • NSF sponsored Advanced Chemistry and Art Workshop (2017)
  • Cancer Center Fellowship, Department of Chemistry, University of Virginia (2012-2013)
  • Warsaw University Postdoctoral International Fellowship to the National Institutes of Health, Bethesda, MD (2012)
  • Outstanding Achievement Award for a Ph.D. Candidate, Department of Chemistry, Warsaw University (PL) (2009-2010)
  • Warsaw University Competitive Select Fellowship for Ph.D. Candidates (2006-2010)
  • Scholarship of the Republic of Poland (2001-2006)