Josh Kelley Visiting Assistant Professor of Biology

Josh Kelley

Howe 413


2008 Ph.D. Biochemistry and Molecular Genetics, University of Virginia

2000 BS Chemistry, University of Virginia


I use biochemistry and computational cell biology to study spatio-temporal regulation of G-protein signaling and gradient tracking in the Baker’s Yeast, Saccharomyces cerevisiae.


Fall 2015

  • BIOL 220 Genetics
  • BIOL 221 Genetics Lab

Selected Publications

1: Kelley JB, Dixit G, Sheetz JB, Venkatapurapu SP, Elston TC, Dohlman HG. RGS
proteins and septins cooperate to promote chemotropism by regulating polar cap
mobility. Curr Biol. 2015 Feb 2;25(3):275-85. doi: 10.1016/j.cub.2014.11.047.
Epub 2015 Jan 15. PubMed PMID: 25601550; PubMed Central PMCID: PMC4318785.

2: Venkatapurapu SP*, Kelley JB*, Dixit G, Pena M, Errede B, Dohlman HG, Elston TC.
Modulation of receptor dynamics by the regulator of G-protein signaling Sst2. Mol
Biol Cell. 2015 Aug 26. pii: mbc.E14-12-1635. [Epub ahead of print] PubMed PMID:

3: Dixit G, Kelley JB, Houser JR, Elston TC, Dohlman HG. Cellular noise
suppression by the regulator of G protein signaling Sst2. Mol Cell. 2014 Jul
3;55(1):85-96. doi: 10.1016/j.molcel.2014.05.019. Epub 2014 Jun 19. PubMed PMID:
24954905; PubMed Central PMCID: PMC4142594.

4: Kelley JB, Datta S, Snow CJ, Chatterjee M, Ni L, Spencer A, Yang CS,
Cubeñas-Potts C, Matunis MJ, Paschal BM. The defective nuclear lamina in
Hutchinson-gilford progeria syndrome disrupts the nucleocytoplasmic Ran gradient
and inhibits nuclear localization of Ubc9. Mol Cell Biol. 2011
Aug;31(16):3378-95. doi: 10.1128/MCB.05087-11. Epub 2011 Jun 13. PubMed PMID:
21670151; PubMed Central PMCID: PMC3147792.

5: Kelley JB, Talley AM, Spencer A, Gioeli D, Paschal BM. Karyopherin alpha7
(KPNA7), a divergent member of the importin alpha family of nuclear import
receptors. BMC Cell Biol. 2010 Aug 11;11:63. doi: 10.1186/1471-2121-11-63. PubMed
PMID: 20701745; PubMed Central PMCID: PMC2929220.