The Bio-Rad Personal Molecular Imager system is a high-resolution laser scanning system for radioisotopic imaging. This system accommodates both large (35 x 43 cm) and small (20 x 25 cm) storage phosphor screens for the imaging and quantitation of 32P, 33P, 35S, 14C, and 3H. Analysis is done using the Quantity One 1-D software package.