
Science Addition A427
The Uffelman group is developing a set of novel polyamide macrocyclic ligands in order to expand the fundamental chemistry and Green Chemistry applications of iron-catalyzed oxidation reactions. Currently we are in our third iteration of ligand syntheses, which has been highly successful. This research program has, to date, involved forty-two different undergraduates, who gain experience in various NMR techniques, IR spectroscopy, inert atmosphere synthetic methods, and organic and inorganic synthesis. Sixteen of these students have done more than one summer of research in the group.
Uffelman, E. S. "Teaching Science in Art: Technical Examination of 17th-Century Dutch Painting as Interdisciplinary Coursework for Science Majors and Nonmajors" J. Chem. Educ. 2007, 83, 1617-1624.
Uffelman, E. S. "A Review of Materials for Teaching Science in Art: Technical Examination of 17th-Century Dutch Painting as Interdisciplinary Course Work for Non-Science and Science Majors" J. Chem. Educ. 2007, October Web Online, 38 pages. http://www.jce.divched.org/Journal/Supplements/index.html.
Uffelman, E. S. "NMR Studies of Polyamide Macrocyclic Tetradentate Ligands and Their Complexes Relevant to Green Chemistry (with Other Inorganic/Organometallic Experiments)" in Modern NMR Spectroscopy in Education; Stockland, R. A.; Rovnyak, D.; Eds.; ACS Symposium Series 969; American Chemical Society: Washington, DC, 2007 300-316.
Uffelman, E. S. "News from Online: Renewable Resources" J. Chem. Educ. 2007, 83, 220-222.
Weng, T-C.; Hsieh, W-Y.; Uffelman, E. S.; Gordon-Wylie, S. W.; Collins, T. J.; Pecoraro, V. L.; Penner-Hahn, J. E. "XANES Evidence Against a Manganyl Species in the S3 state of the Oxygen Evolving Complex" J. Am. Chem. Soc. 2004, 126, 8070-8071.
Uffelman, E. S. "News from Online: Green Chemistry" J. Chem. Educ. 2004, 81, 172-176.
Uffelman, E. S.; Doherty, J. R.; Schulze, C.; Burke, A. L.; Bonnema, K.; Watson, T. T.; Lee, D. W., III "Microscale Syntheses, Reactions, and 1H NMR Spectroscopic Investigations of Square Planar Macrocyclic Tetraamido-N Co(III) Complexes Relevant to Green Chemistry" J. Chem. Educ. 2004, 81, 325-329.
Uffelman, E. S.; Doherty, J. R.; Schulze, C.; Burke, A. L.; Bonnema, K.; Watson, T. T.; Lee, D. W., III "Microscale Syntheses, Reactions, and 1H NMR Spectroscopic Investigations of Square Planar Macrocyclic Tetraamido-N Cu(III) Complexes Relevant to Green Chemistry" J. Chem. Educ. 2004, 81, 182-185.
Uffelman, E. S.; Cox, E. H.; Goehring, J. B.; Lorig, T. S.; Davis, C. M. "An NMR-Smell Module for the First Semester General Chemistry Laboratory" J. Chem. Educ., 2003, 80, 1368-1371.
Rorrer, L. C.; Hopkins, S. D.; Connors, M. K.; Lee, D. W.,III; Smith, M. V.; Rhodes, H. J.; Uffelman, E. S. "A Convenient New Route to Tetradentate and Pentadentate Macrocyclic Ligands" Organic Letters 1999, 1, 1157-1159.
France, M. B.; Uffelman, E. S. "Ring-Opening Metathesis Polymerization with a Well-Defined Rutheniium Carbene Complex: An Experiement for the Undergraduate Inorganic or Polymer Laboratory" J. Chem. Educ., 1999, 5, 661-665.
Bartos, M. J.; Gordon-Wylie, S. W.; Fox, B. G.; Wright, L. J.; Weintraub, S. T.; Kauffman, K. E.; Münck, E.; Kosta, K. L.; Uffelman, E. S.; Rickard, C. E. F.; Noon, K. R.; Collins, T. J.; "Designing Ligands to Achieve Robust Oxidation Catalysts. Iron Based Systems" Coord. Chem. Rev. 1998, 174, 361-390.
Collins, T. J.; Bartos, M. J.; Gordon-Wylie, S. W.; Fox, B. G.; Kauffmann, K. E.; Münk, E.; Rickard, C. E. F.; Weintraub, S. T.; Uffelman, E. S.; Wright, L. "Designing Ligands to Achieve Robust Atom-Transfer Oxidation Catalysts," J. Inorg. Biochem. 1995, 59, 318-319.
Collman, J. P.; Zhang, X.; Herrmann, P. C.; Uffelman, E. S.; Boitrel, B.; Straumanis, A.; Brauman, J. I. "Congruent Multiple Michael Addition for the Synthesis of Biometric Heme Analogues," J. Am. Chem. Soc. 1994, 116, 2681-2682.
Collman, J. P.; Zhang, X.; Lee, V. J.; Uffelman, E. S.; Brauman, J. I. "Regioselective and Enantioselective Epoxidation Catalyzed by Metalloporphyrins," Science (Washington, D. C.) 1993, 261, 1404-1411
Collins, T. J.; Kostka, K. L.; Uffelman, E. S.; Weinberger, T. "Design, Synthesis, and Structure of a Macrocyclic Tetraamide That Stabilizes High-Valent Middle and Later Transition Metals," Inorg. Chem. 1991, 30, 4204-4210
Collins, T. J.; Nichols, T. R.; Uffelman, E. S. "A Square-Planar Nickel(III) Complex of an Innocent Ligand System," J. Am. Chem. Soc. 1991, 113, 4708-4709.
Collins, T. J.; Powell, R. D.; Slebodnick, C.; Uffelman, E. S. "Stable Highly Oxidizing Cobalt complexes of Macrocyclic Tetraamide Ligands," J. Am. Chem. Soc. 1991, 113, 8419-8425.
Collins, T. J.; Kostka, K. L.; Münk, E.; Uffelman, E. S. "Stabilization of Mononuclear Five-Coordinate Iron (IV)," J. Am. Chem. Soc. 1990, 112, 5637-5639.
Collins, T. J.; Powell, R. D.; Slebodnick, C.; Uffelman, E. S. "A Water-Stable Manganese(V)-Oxo Complex: Definitive Assignment of a v(Mn-O) Triple Bond Infrared Vibration," J. Am. Chem. Soc. 1990, 112, 899-901.
Collins, T. J.; Slebodnick, C.; Uffelman, E. S. "Chromium(V)-Oxo Complexes of Macrocyclic Tetraamido-N Ligands Tailored for Highly Oxidized Middle Transition Metal Complexes: A 18O-Labelling Reagent and a Structure with Four Nonplanar Amides," Inorg. Chem. 1990, 29, 3432-3436.
Collins, T. J.; Uffelman, E. S. "The First Macrocyclic Square-Planar Cobalt(III) Complex Relieves Ring Strain by Forming a Nonplanar Amide," Angew. Chem. Int. Ed. Engl. 1989, 28, 1509-1511.
Novel undergraduate experiments involving NMR methodology or Green Chemistry are developed.
In addition, technical analysis of 17th century Dutch painting is used to teach an interdisciplinary non-science majors course at the interface of chemistry, physics, analytical instrumentation, history, economics, and religion. The course takes students abroad to The Netherlands for three weeks.
Forty-seven at W&L---several for more than one summer or semester (Tamara Hopkins, T. R. Kinsey, Ryan Aday, Matthew Smith, Robert Eison, Anna Mirk, Hilary Rhodes, Jesse Taylor, Holly Layman, Charity Forstmann, Daniel Lee, Anne McElhaney, Jon Doherty, Leonard Rorrer, Carl Schulze, Stephen Hopkins, Michele Connors, Robert Hughes, Alison Cartwright, Ashley Shreves, Tom Stoklasek, Kristen Bonnema, Amy Burke, Gary Davis, Mac Everist, Tanya Watson, Ashley Acker, Bryan Carmody, Andrew Thomas, Marisa Meyer, Johnathan Coleman, Nana Ohene-Baah, Jessica Lloyd, Matthew Reilley, Jared Meyer, Emily Binns, Christopher Diebold, Carly Levin, Scot Pittman, Robert Whitener, Kehvon Clark, Elizabeth Webb, Zachary Haulsee, M. Ian Childers, Kendall Massengill, Carolyn Small, Allison Lemon)